Preferred Label : Doxorubicin-Eluting Beads;
NCIt definition : A drug-device combination product consisting of small polymeric beads impregnated
with the anthracycline antibiotic doxorubicin with potential antineoplastic activity.
The beads consist of polyvinyl alcohol (PVA) microspheres modified with sulfonic acid
groups and loaded with doxorubicin. During transarterial chemoembolization (TACE),
doxorubicin-eluting beads embolize to the tumor vasculature and release cytotoxic
doxorubicin, which may result in both ischemic necrosis of tumor tissue due to mechanical
blockage of the tumor vasculature and doxorubicin-mediated inhibition of tumor cell
proliferation.;
NCI Metathesaurus CUI : CL413528;
Origin ID : C82419;
UMLS CUI : C2826165;
Semantic type(s)
- concept_is_in_subset
- has_target
