Preferred Label : MUC1 Peptide-Poly-ICLC Vaccine;
NCIt synonyms : MUC1 Peptide Vaccine-Poly-ICLC Adjuvant;
NCIt definition : A vaccine preparation containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC
with potential immunostimulatory and antineoplastic activities. Upon administration,
MUC1 peptide-poly-ICLC adjuvant vaccine may induce the host immune system to mount
a cytotoxic T cell response against MUC1-expressing tumor cells. MUC1, a tumor associated
antigen normally present on the lining of the human colon, may be overexpressed and/or
mutated in a variety of cancer cell types. The adjuvant poly-ICLC, a ligand for toll-like
receptor-3, induces the release of cytokines which may help boost the immune response
against MUC1.;
Origin ID : C82417;
UMLS CUI : C2826163;
Semantic type(s)
- concept_is_in_subset
- has_target
