NCIt definition : A traditional Chinese medicine (TCM) containing a water soluble Bufo toad skin extract
that includes the cardiac glycosides bufalin, cinobufagin and resibufogenin with potential
antineoplastic and antiangiogenic activities. Although the exact mechanism of action
of this TCM has yet to be fully elucidated, huachansu, which may be administered in
an injectable form, may induce cell cycle arrest and apoptosis by suppressing the
expression of anti-apoptotic proteins, such as Bcl-2, while inducing the expression
of pro-apoptotic proteins, such as BAX.;
Currated CISMeF NLP mapping