" /> Immunocytokine NHS-IL2-LT - CISMeF





Preferred Label : Immunocytokine NHS-IL2-LT;

NCIt synonyms : Ch.14.18-IL2;

NCIt related terms : SELECTIKINE; Interleukin-2 Fusion Protein MSB0010445;

NCIt definition : A fusion protein consisting of a mouse-human chimeric antibody directed against DNA released by necrotic tumor cells fused to two molecules of a genetically modified human interleukin-2 (IL-2) with potential antineoplastic activity. Upon administration, the antibody moiety of immunocytokine NHS-IL2-LT binds to DNA released by necrotic tumor cells located primarily at the core of necrotic solid tumors, delivering the IL-2 moiety. In turn, the IL-2 moiety of this agent activates the immune system to mount a cytotoxic T lymphocyte response against nearby tumor cells.;

UNII : EI74F49ZLJ;

CAS number : 1223034-72-7;

Drug name : Selectikine;

Molecule name : EMD 521873; NHS-IL2; MSB0010445;

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09/05/2025


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