Bone Metastasis Targeting Peptide-11

Preferred Label : Bone Metastasis Targeting Peptide-11;

NCIt definition : A peptide that mimics naturally occurring interleukin-11 (IL-11) with interleukin receptor binding activity. Upon administration, bone metastasis targeting peptide-11 (BMTP-11) binds to interleukin-11 receptor alpha (IL-11Ra) BMTP-11. This agent might be used to deliver therapeutic agents specifically to IL-11Ra-expressing tumor cells while sparing normal cells. IL-11Ra is a cell surface receptor that may be overexpressed by osteosarcoma cells and by prostate cancer cells in prostate cancer bone metastases.;

Molecule name : BMTP-11;

Details

Origin ID

C82370;

UMLS CUI

C2830059;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bone metastasis-targeting peptidomimetic-11 [MeSH Supplementary Concept]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Interleukin-11 Receptor Subunit Alpha [NCIt concept]

Keyword's position in hierarchy(ies) :

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