Preferred Label : Leucine-Enhanced Essential Amino Acid Dietary Supplement;
NCIt synonyms : Leucine-Enhanced Essential Amino Acids;
NCIt definition : An orally bioavailable leucine enriched essential amino acid dietary supplement with
potential anti-cachexia activity. Leucine-enhanced essential amino acid nutritional
supplement may stimulate the mammalian target of rapamycin (mTOR) signaling pathway,
which may promote protein synthesis in muscle cells. Although the exact mechanism
by which leucine and other essential amino acids stimulate mTOR has yet to be fully
elucidated, leucine may stimulate mTOR by inhibiting adenosine monophosphate protein
kinase (AMPK), which negatively controls mTOR signaling.;
NCI Metathesaurus CUI : CL408637;
Origin ID : C82357;
UMLS CUI : C2826119;
Semantic type(s)
- concept_is_in_subset
