" /> Onartuzumab - CISMeF





Preferred Label : Onartuzumab;

NCIt synonyms : Anti-MET Monoclonal Antibody MetMAb;

NCIt definition : A humanized monovalent monoclonal antibody directed against the hepatocyte growth factor receptor (c-Met) with potential antineoplastic activity. Anti-MET monoclonal antibody MetMAb binds to the extracellular domain of c-Met, preventing the binding of its ligand, hepatocyte growth factor (HGF); the activation of the c-Met signaling pathway is thus inhibited, which may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase, is overexpressed on the cell surfaces of a variety of cancer cell types and may play a key role in their proliferation, invasion and survival.;

UNII : MS1J9720WC;

CAS number : 1133766-06-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1133766-06-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MetMAb; OA-5D5; PRO 143966; RO5490258;

Codes from synonyms : 370;

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Keyword's position in hierarchy(ies) : arborescence

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14/05/2024


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