Prasugrel Hydrochloride

Preferred Label : Prasugrel Hydrochloride;

NCIt definition : The hydrochloride salt form of prasugrel, an orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.;

UNII : G89JQ59I13;

InChIKey : JALHGCPDPSNJNY-UHFFFAOYSA-N;

CAS number : 389574-19-0;

Drug name : Effient; Efient;

Chemical formula : C20H20FNO3S.HCl;

Détails

Origin ID

C81571;

UMLS CUI

C2683417;

CISMeF manual mappings
- Prasugrel Hydrochloride [MeSH Descriptor]
Currated CISMeF NLP mapping
- Prasugrel Hydrochloride [MeSH concept]
- Prasugrel hydrochloride [SMS substance]
- Prasugrel hydrochloride (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Prasugrel Hydrochloride [MeSH Descriptor]
- Prasugrel hydrochloride (substance) [SNOMED CT concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Prasugrel [NCIt concept]
is_salt_form_of
- Prasugrel [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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