NCIt definition : An orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration,
the active metabolite of prasugrel targets and irreversibly binds to the platelet
receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its
receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa,
fibrinogen binding to platelets and platelet adhesion and aggregation. This results
in increased bleeding time.;