Antihemophilic Factor, Human Recombinant

Preferred Label : Antihemophilic Factor, Human Recombinant;

NCIt synonyms : Factor VIII; FVIII; Antihemophilic Factor Human Recombinant;

NCIt definition : The recombinant form of human antihemophilic factor (AH)) (Factor VIII) with coagulation promoting activity. Antihemophilic factor binds to factor IXa in the coagulation cascade along with calcium and phospholipid. This complex converts factor X to the activated form, factor Xa. In turn, factor Xa/Va complex activates thrombin, which cleaves fibrinogen into fibrin, eventually resulting in blood clot formation.;

UNII : P89DR4NY54;

CAS number : 139076-62-3;

Details

Origin ID

C81123;

UMLS CUI

C2732002;

Automatic exact mappings (from CISMeF team)
- Antihemophilic globulin [FMA entity]
- Coagulation factor VII level [MedDRA Preferred Term]
- Coagulation factor VII level low [MedDRA LLT]
- Coagulation factor VIII [OMIM gene]
- Coagulation factor VIII [ICD-11 Extension code]
- Coagulation factor VIII level low [MedDRA LLT]
- Factor VIII [PASCAL descriptor]
- Factor VIII given [LOINC component]
- coagulation factor VIII [ORDO Gene]
- factor VII [MeSH concept]
- factor VII [MeSH Descriptor]
- factor VIII [Blood Transfusion thesaurus concept]
- factor VIIa [MeSH concept]
Currated CISMeF NLP mapping
- Coagulation factor VIII (substance) [SNOMED CT concept]
- Coagulation factor VIII activity [LOINC component]
- Coagulation factor VIII level [MedDRA Preferred Term]
- Factor VIII [LOINC component]
- blood-coagulation factor viii [Substance BNPC]
- coagulation factor viii [SNOMED Notion]
- factor VIII [MeSH Descriptor]
- factor VIII [MeSH concept]
False automatic mappings
- factor VIII (des-797-1562) [MeSH concept]
- factor VIII (des-797-1562) [MeSH Supplementary Concept]
- factor VIIa [MeSH Descriptor]
See also inter- (CISMeF)
- Coagulation factor VIII [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DNA factor VIII (product) [Inactive SNOMED CT concept]
- Recombinant antihemophilic factor agent (product) [Inactive SNOMED CT concept]
- Recombinant antihemophilic factor agent (substance) [Inactive SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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