Gadofosveset - CISMeF

Preferred Label : Gadofosveset;

NCIt synonyms : EPIX;

NCIt definition : An injectable, intravascular, amphiphilic gadolinium-based contrast agent (GBCA) used with magnetic resonance angiography (MRA) imaging. Gadofosveset is a stable gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) chelate derivative with a diphenylcyclohexylphosphate group. Upon injection, gadofosveset binds reversibly to endogenous serum albumin which increases its intravascular retention time compared to non-protein binding contrast agents. The serum albumin binding also increases T1-relaxivity of gadofosveset. This produces an increase in signal intensity of blood, thereby enhancing the visualization of blood vessels upon MRA and may aid in the diagnosis of certain blood vessels and heart disorders.;

UNII : E65RW73PHS;

InChIKey : ZSDLYSDDELEVDD-UFTMZEDQSA-K;

CAS number : 201688-00-8;

Chemical formula : C33H38N3O14P.3H.Gd;

Details

Origin ID

C81056;

UMLS CUI

C1698893;

Automatic exact mappings (from CISMeF team)
- Gadofosveset [ICD-11 Extension code]
- Product containing gadofosveset (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Gadofosveset (substance) [SNOMED CT concept]
- Product containing gadofosveset (medicinal product) [SNOMED CT concept]
- gadofosveset [ATC Code]
Validated automatic mappings to BTNT
- gadofosveset [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Gadofosveset Trisodium [NCIt concept]
is_free_acid_or_base_form_of
- Gadofosveset Trisodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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