Noscapine - CISMeF

Preferred Label : Noscapine;

NCIt definition : A phthalide isoquinoline non-narcotic alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities. Noscapine exerts its antitussive effects through the activation of sigma opioid receptors. This agent appears to exert its antimitotic effect by binding to tubulin, resulting in a disruption of microtubule assembly dynamics and subsequently, the inhibition of mitosis and tumor cell death.;

UNII : 8V32U4AOQU;

InChIKey : AKNNEGZIBPJZJG-MSOLQXFVSA-N;

CAS number : 128-62-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 128-62-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C22H23NO7;

NSC code : 5366;

Details

Origin ID

C80589;

UMLS CUI

C0028426;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Noscapine [ICD-11 Extension code]
- Noscapine (substance) [SNOMED CT concept]
- Product containing noscapine (medicinal product) [SNOMED CT concept]
- noscapine [ATC Code]
- noscapine [Substance BNPC]
- noscapine [MeSH concept]
- noscapine [MeSH Descriptor]
- noscapine [SNOMED Notion]
Validated automatic mappings to BTNT
- noscapine [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Microtubule Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Noscapine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Noscapine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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