Preferred Label : Cytomegalovirus IE-1-specific Cytotoxic T Lymphocytes;
NCIt synonyms : CMV IE-1-specific CTL;
NCIt definition : Cytotoxic T-lymphocytes (CTLs), specifically reactive to the cytomegalovirus (CMV)
immediate early-1 (IE-1) protein, with immunomodulating activity. Adoptive immunotherapy
with cytomegalovirus IE-1-specific cytotoxic T lymphocytes may help reconstitute CD8
cytomegalovirus-specific CTL responses in CMV-infected immunocompromised hosts. IE-1
is one of the first CMV antigens expressed by CMV-infected cells, predominantly inducing
a CD8 CTL response.;
NCI Metathesaurus CUI : CL388394;
Origin ID : C80052;
UMLS CUI : C2699542;
Semantic type(s)
- concept_is_in_subset
