Butoconazole - CISMeF

Preferred Label : Butoconazole;

NCIt synonyms : ( -)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole;

NCIt definition : A synthetic imidazole derivative with fungistatic properties. Butoconazole interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butaconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms.;

UNII : 0Q771797PH;

InChIKey : SWLMUYACZKCSHZ-UHFFFAOYSA-N;

CAS number : 64872-76-0;

Molecule name : RS 35887-10-3;

Chemical formula : C19H17Cl3N2S;

ChEBI ID : CHEBI:3240;

Details

Origin ID

C79927;

UMLS CUI

C0054259;

Automatic exact mappings (from CISMeF team)
- Butoconazole (nitrate) [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Butoconazole (substance) [SNOMED CT concept]
- Product containing butoconazole (medicinal product) [SNOMED CT concept]
- butoconazole [ATC Code]
- butoconazole [MeSH concept]
- butoconazole [SNOMED Notion]
- butoconazole [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- butoconazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Butoconazole Nitrate [NCIt concept]
is_free_acid_or_base_form_of
- Butoconazole Nitrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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