NCIt definition : The nitrate salt form of butaconazole, a synthetic imidazole derivative with fungistatic
properties. Butoconazole nitrate interferes with steroid biosynthesis by inhibiting
the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane
lipid composition. This alters cell permeability and leads to growth inhibition. Butaconazole
nitrate is active against many dermatophytes and yeasts. It also contains antibacterial
effects against some gram-positive organisms.;