Preferred Label : Carbenicillin Phenyl;
NCIt synonyms : (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((2-phenoxycarbonyl)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptan-2-carbonsaeure;
NCIt definition : The phenyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative
with antibacterial activity. Following absorption, carbenicillin phenyl sodium is
rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding
proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby
preventing the cross-linkage of peptidoglycans, which are critical components of the
bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually
causing bacterial cell lysis.;
UNII : 9UU4XDB74X;
InChIKey : NZDASSHFKWDBBU-KVMCETHSSA-N;
CAS number : 27025-49-6;
Chemical formula : C23H22N2O6S;
ChEBI ID : CHEBI:3414;
Origin ID : C79761;
UMLS CUI : C2698988;
Currated CISMeF NLP mapping
See also inter- (CISMeF)
Semantic type(s)
Validated automatic mappings to BTNT
concept_is_in_subset