Carbenicillin Phenyl

Preferred Label : Carbenicillin Phenyl;

NCIt synonyms : (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((2-phenoxycarbonyl)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptan-2-carbonsaeure;

NCIt definition : The phenyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Following absorption, carbenicillin phenyl sodium is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.;

UNII : 9UU4XDB74X;

InChIKey : NZDASSHFKWDBBU-KVMCETHSSA-N;

CAS number : 27025-49-6;

Chemical formula : C23H22N2O6S;

ChEBI ID : CHEBI:3414;

Détails

Origin ID

C79761;

UMLS CUI

C2698988;

Currated CISMeF NLP mapping
- Carfecillin [ICD-11 Extension code]
- Carfecillin [ICHI extension code]
- Carfecillin [SMS substance]
- Carfecillin (substance) [SNOMED CT concept]
- carfecillin [MeSH Descriptor]
- carfecillin [MeSH concept]
- carfecillin [Substance BNPC]
See also inter- (CISMeF)
- Product containing carfecillin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- carfecillin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Carbenicillin Phenyl Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Carbenicillin Phenyl Sodium [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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