Preferred Label : Carbenicillin Phenyl Sodium;
NCIt synonyms : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((1,3-dioxo-3-phenoxy-2-phenylpropyl)amino)-3,3-dimethyl-7-oxo-,
monosodium salt, (2S-(2alpha,5alpha,6beta));
NCIt definition : The sodium salt of the phenyl ester of carbenicillin, a broad-spectrum, semisynthetic
penicillin derivative with antibacterial activity. Following absorption, carbenicillin
phenyl sodium is rapidly hydrolyzed to the active carbenicillin, which binds to and
inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the
bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which
are critical components of the bacterial cell wall. This leads to a weakening of the
bacterial cell wall, eventually causing bacterial cell lysis.;
UNII : 18N5JP36GY;
InChIKey : JXSBZDNBNJTHBJ-JPZUGYNPSA-M;
CAS number : 21649-57-0;
Drug name : Uticillin;
Chemical formula : C23H21N2O6S.Na;
ChEBI ID : CHEBI:34612;
Origin ID : C79421;
UMLS CUI : C0085959;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
