Preferred Label : Tetrodotoxin;
NCIt synonyms : TTX; Babylonia Japonica Toxin 1; 5,9:7,10a-Dimethano-10aH-(1,3)dioxocino(6,5-d)pyrimidine-4,7,10,11,12-pentol, Octahydro-12-(hydroxymethyl)-2-imino-;
NCIt definition : A neurotoxin with potential analgesic activity. Tetrodotoxin binds to the pores of
fast voltage-gated fast sodium channels in nerve cell membranes, inhibiting nerve
action potentials and blocking nerve transmission. Although found in various species
of fish (such as the pufferfish), newts, frogs, flatworms, and crabs, tetrodotoxin,
for which there is no known antidote, is actually produced by bacteria such as Vibrio
alginolyticus, Pseudoalteromonas tetraodonis, and other vibrio and pseudomonas bacterial
species.;
Alternative definition : CDISC: The biotoxin tetrodotoxin.;
UNII : 3KUM2721U9;
InChIKey : CFMYXEVWODSLAX-QOZOJKKESA-N;
CAS number : 4368-28-9;
Drug name : Tectin;
ChEBI ID : CHEBI:9506;
Origin ID : C78845;
UMLS CUI : C0039705;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
