Preferred Label : Iofolastat I123;
NCIt synonyms : 123-I-MIP-1072; Iodine I 123 MIP-1072; L-Glutamic Acid, N-((((1S)-1-carboxy-5-(((4-(iodo-123i)phenyl)methyl)amino)pentyl)amino)carbonyl)-; N-(((1S)-1-carboxy-5-(((4-((Sup 123)i)iodophenyl)methyl)amino)pentyl)carbamoyl)-L-glutamic
Acid;
NCIt related terms : IOFOLASTAT I-123;
NCIt definition : An iodine 123-radiolabeled small molecule that exhibits high affinity for prostate-specific
membrane antigen (PSMA) with potential use in molecular imaging. Iofolastat I123,
a radiolabeled glutamate-urea-lysine analogue, selectively binds PSMA, which allows
imaging of PSMA-expressing prostate cancer cells with gamma scintigraph. PSMA is a
transmembrane glycoprotein highly expressed by malignant prostate epithelial cells
and vascular endothelial cells of various solid tumors.;
UNII : AQF0A29T2V;
CAS number : 949575-24-0;
NCI Metathesaurus CUI : CL387748;
Origin ID : C78827;
UMLS CUI : C4519136;
Semantic type(s)
- concept_is_in_subset
- has_target
