Methoxyamine - CISMeF

Preferred Label : Methoxyamine;

NCIt synonyms : TRC102 Base;

NCIt definition : An orally bioavailable small molecule inhibitor with potential adjuvant activity. Methoxyamine covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. This agent may potentiate the anti-tumor activity of alkylating agents.;

UNII : 9TZH4WY30J;

InChIKey : GMPKIPWJBDOURN-UHFFFAOYSA-N;

CAS number : 67-62-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 67-62-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : CH5NO;

Details

Origin ID

C78084;

UMLS CUI

C0066156;

Currated CISMeF NLP mapping
- methoxyamine [Substance BNPC]
- methoxyamine [MeSH concept]
- methoxyamine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- methoxyamine [Substance BNPC]
- methoxyamine [MeSH concept]
- methoxyamine [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Methoxyamine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Methoxyamine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients