Bevirimat - CISMeF

Preferred Label : Bevirimat;

NCIt synonyms : 3-O-(3',3'-dimethylsuccinyl) betulinic acid;

NCIt definition : A drug derived from a betulinic acid-like compound, first isolated from the Chinese herb Syzygium claviflorum, with activity against human immunodeficiency virus (HIV). Bevirimat acts by binding to the Gag capsid precursor protein and blocking its conversion to mature capsid protein by protease cleavage. It potently inhibits replication in both wild-type and drug-resistant (reverse transciptase or protease) HIV-1 isolates.;

UNII : S125DW66N8;

CAS number : 174022-42-5;

Molecule name : PA-457; MPC-4326;

Chemical formula : C36H56O6;

Details

Origin ID

C78044;

UMLS CUI

C1433069;

Currated CISMeF NLP mapping
- bevirimat [MeSH concept]
- bevirimat [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bevirimat [MeSH Supplementary Concept]
- bevirimat [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Bevirimat Dimeglumine [NCIt concept]
is_free_acid_or_base_form_of
- Bevirimat Dimeglumine [NCIt concept]

Keyword's position in hierarchy(ies) :

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