Aplaviroc - CISMeF

Preferred Label : Aplaviroc;

NCIt synonyms : 4-(4-{[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl}phenoxy)benzoic acid; AK602; GSK-87314;

NCIt definition : A C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against HIV-1. Aplaviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.;

UNII : 98B425P30V;

InChIKey : GWNOTCOIYUNTQP-FQLXRVMXSA-N;

CAS number : 461443-59-4;

Chemical formula : C33H43N3O6;

Details

Origin ID

C78043;

UMLS CUI

C1567923;

Currated CISMeF NLP mapping
- aplaviroc [MeSH concept]
- aplaviroc [MeSH Supplementary Concept]
See also inter- (CISMeF)
- 4-((4-((3R)-1-butyl-3-((1R)) cyclohexylhy-droxymethyl)-2,5-dioxo-1,4,9-triazaspiro(5.5)undec-9-yl methyl)phenoxy)benzoic acid hydrochloride [MeSH Supplementary Concept]
- AK602 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- aplaviroc [MeSH Supplementary Concept]
- aplaviroc [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Aplaviroc Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Aplaviroc Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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