Rivaroxaban - CISMeF

Preferred Label : Rivaroxaban;

NCIt synonyms : 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)- 1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide;

NCIt definition : An orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels.;

UNII : 9NDF7JZ4M3;

InChIKey : KGFYHTZWPPHNLQ-AWEZNQCLSA-N;

CAS number : 366789-02-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 366789-02-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Xarelto;

Molecule name : BAY 59-7939;

Chemical formula : C19H18ClN3O5S;

Codes from synonyms : 448;

Details

Origin ID

C77995;

UMLS CUI

C1739768;

Automatic exact mappings (from CISMeF team)
- Rivaroxaban [ICD-11 Extension code]
CISMeF manual mappings
- Rivaroxaban [MeSH Descriptor]
- Rivaroxaban (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing rivaroxaban (medicinal product) [SNOMED CT concept]
- Rivaroxaban [MeSH Descriptor]
- Rivaroxaban [LOINC component]
- Rivaroxaban (substance) [SNOMED CT concept]
- rivaroxaban [ATC Code]
- rivaroxaban [Substance BNPC]
- rivaroxaban [International Nonproprietary Name]
- rivaroxaban [MeSH concept]
Validated automatic mappings to BTNT
- rivaroxaban [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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