NCIt definition : An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential
antineoplastic activity. c-Met inhibitor JNJ-38877605 selectively inhibits c-Met,
a receptor tyrosine kinase (RTK) involved in cancer cell survival and invasiveness,
and tumor angiogenesis. c-Met is also known as hepatocyte growth factor receptor (HGFR).;