Prolactin - CISMeF

Preferred Label : Prolactin;

NCIt synonyms : PRL; Growth Hormone A1; Decidual Prolactin;

NCIt definition : Prolactin (227 aa, 26 kDa) is encoded by the human PRL gene. This protein is involved in the promotion of lactation in the mammary gland.;

Alternative definition : NCI-GLOSS: A hormone that is made by the pituitary gland (a pea-sized organ in the center of the brain). Prolactin causes a woman's breasts to make milk during and after pregnancy, and has many other effects in the body.;

NCIt note : Prolactin proprotein is cleaved into an active peptide comprised of amino acid residues 29-227. (UniProt);

Codes from synonyms : 01229; CDR0000476644;

Details

Origin ID

C778;

UMLS CUI

C5441683;

Automatic exact mappings (from CISMeF team)
- Prolactin [OMIM gene]
- Prolactin [ICHI extension code]
- big big prolactin [MeSH concept]
- big prolactin [MeSH concept]
- prolactin [HGNC gene]
- prolactin [EMDN type]
- prolactin [medical devices type]
- prolactin receptor binding [GO term]
- prolactin, polymeric [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Mammotropin [FMA entity]
- Prolactin [ICD-11 Extension code]
- Prolactin [FMA entity]
- Prolactin [LOINC component]
- Prolactin [MedDRA LLT]
- Prolactin (substance) [SNOMED CT concept]
- prolactin [MeSH Descriptor]
- prolactin [MeSH concept]
- prolactin [SNOMED Notion]
OMIM relation
- Prolactin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
UMLS correspondences (same concept)
- Mammotropin [FMA entity]
- Product containing prolactin (medicinal product) [SNOMED CT concept]
- Prolactin [LOINC part]
- Prolactin [FMA entity]
- Prolactin [LOINC component]
- Prolactin (substance) [SNOMED CT concept]
- prolactin [SNOMED Notion]
- prolactin [MeSH Descriptor]
- prolactin [MeSH concept]
- prolactin preparation [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- PRL Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_expressed_in_tissue
- Anterior Lobe of the Pituitary Gland [NCIt concept]
gene_product_has_biochemical_function
- Pituitary Hormone [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Secretion [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Reproduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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