Bisantrene Hydrochloride

Preferred Label : Bisantrene Hydrochloride;

NCIt synonyms : 9,10-Anthracenedicarboxaldehyde Bis(2-imidazolin-2-yl)hydrazone Dihydrochloride; 9,10-Anthracenedicarboxakdehyde Bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] Dihydrochloride; Orange Crush; Bisantrene Dihydrochloride; 9,10,Anthracenedicarboxaldehyde Dihydrochloride;

NCIt related terms : CL 216942;

NCIt definition : The hydrochloride salt of an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the helical structure of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity.;

UNII : 74GNV897RO;

InChIKey : KINULKKPVJYRON-PVNXHVEDSA-N;

CAS number : 71439-68-4;

Drug name : Zantrene;

Molecule name : CL-216942;

Chemical formula : C22H22N8.2HCl;

Codes from synonyms : NSC0337766;

Details

Origin ID

C77218;

UMLS CUI

C0955176;

Currated CISMeF NLP mapping
- bisantrene dihydrochloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bisantrene dihydrochloride [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Bisantrene [NCIt concept]
is_salt_form_of
- Bisantrene [NCIt concept]

Keyword's position in hierarchy(ies) :

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