Preferred Label : Bisantrene Hydrochloride;
NCIt synonyms : 9,10-Anthracenedicarboxaldehyde Bis(2-imidazolin-2-yl)hydrazone Dihydrochloride; 9,10-Anthracenedicarboxakdehyde Bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] Dihydrochloride; Orange Crush; Bisantrene Dihydrochloride; 9,10,Anthracenedicarboxaldehyde Dihydrochloride;
NCIt related terms : CL 216942;
NCIt definition : The hydrochloride salt of an anthracenyl bishydrazone with antineoplastic activity.
Bisantrene intercalates with and disrupts the helical structure of DNA, resulting
in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication.
This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not
exhibit cardiotoxicity.;
UNII : 74GNV897RO;
InChIKey : KINULKKPVJYRON-PVNXHVEDSA-N;
CAS number : 71439-68-4;
Drug name : Zantrene;
Molecule name : CL-216942;
Chemical formula : C22H22N8.2HCl;
Codes from synonyms : NSC0337766;
Origin ID : C77218;
UMLS CUI : C0955176;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
