NCIt definition : The benzathine salt form of a semisynthetic beta-lactamase resistant penicillin antibiotic
with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding
proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby
preventing the cross-linkage of peptidoglycans, which are critical components of the
bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually
causing bacterial cell lysis.;