Cloxacillin - CISMeF

Preferred Label : Cloxacillin;

NCIt definition : A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.;

UNII : O6X5QGC2VB;

InChIKey : LQOLIRLGBULYKD-JKIFEVAISA-N;

CAS number : 61-72-3;

Chemical formula : C19H18ClN3O5S;

ChEBI ID : CHEBI:49566;

Details

Origin ID

C61688;

UMLS CUI

C0009077;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cloxacillin [ICD-11 Extension code]
- Cloxacillin [LOINC component]
- Cloxacillin (substance) [SNOMED CT concept]
- Product containing cloxacillin (medicinal product) [SNOMED CT concept]
- cloxacillin [ATC Code]
- cloxacillin [Substance BNPC]
- cloxacillin [MeSH concept]
- cloxacillin [MeSH Descriptor]
- cloxacillin [SNOMED Notion]
Validated automatic mappings to BTNT
- cloxacillin [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Cloxacillin Benzathine [NCIt concept]
- Cloxacillin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Cloxacillin Benzathine [NCIt concept]
- Cloxacillin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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