" /> Tirofiban - CISMeF





Preferred Label : Tirofiban;

NCIt definition : A non-peptide tyrosine derivative, with anticoagulant activity. Upon administration, tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. This prevents the GP IIb/IIIa receptor complex-mediated activation of adenylyl cyclase. This results in decreased levels of cAMP, interferes with the platelet membrane function and subsequent platelet-platelet interaction, prevents the release of platelet granule constituents and prolongs bleeding time.;

UNII : GGX234SI5H;

InChIKey : COKMIXFXJJXBQG-NRFANRHFSA-N;

CAS number : 144494-65-5;

Chemical formula : C22H36N2O5S;

ChEBI ID : CHEBI:9605;

Codes from synonyms : 497;

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04/05/2025


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