" /> Tirofiban Hydrochloride - CISMeF





Preferred Label : Tirofiban Hydrochloride;

NCIt synonyms : Tirofiban Hydrochloride Monohydrate; N-(Butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-L-tyrosine Monohydrochloride;

NCIt definition : The hydrochloride salt form of tirofiban, a non-peptide tyrosine derivative with anticoagulant property. Tirofiban antagonizes fibrinogen binding to the platelet cell surface receptor, glycoprotein (GP) IIb/IIIA complex, one of the two purinergic receptors activated by ADP. The antagonism prevents adenylyl cyclase activation, which mediated via GP IIb/IIIa receptor complex, and results in decreased levels of cAMP and thereby interferes with platelet membrane function and subsequent platelet-platelet interaction, release of platelet granule constituents and prolongation of bleeding time.;

UNII : 6H925F8O5J;

InChIKey : HWAAPJPFZPHHBC-FGJQBABTSA-N;

CAS number : 150915-40-5;

Drug name : Aggrastat;

Molecule name : MK 383;

Chemical formula : C22H36N2O5S.HCl.H2O;

ChEBI ID : CHEBI:9606;

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10/05/2025


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