Vardenafil Hydrochloride Trihydrate

Preferred Label : Vardenafil Hydrochloride Trihydrate;

NCIt synonyms : Vardenafil Hydrochloride;

NCIt definition : The hydrochloride salt form of vardenafil, a benzenesulfonamide derivative and phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Vardenafil selectively inhibits PDE5, thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, thereby prolonging penile erection.;

UNII : 5M8S2CU0TS;

InChIKey : FBCDRHDULQYRTB-UHFFFAOYSA-N;

CAS number : 330808-88-3;

Drug name : Levitra;

Chemical formula : C23H32N6O4S.ClH.3H2O;

Details

Origin ID

C76318;

UMLS CUI

C1960918;

Automatic exact mappings (from CISMeF team)
- vardenafil dihydrochloride [MeSH concept]
Currated CISMeF NLP mapping
- Vardenafil hydrochloride trihydrate [SMS substance]
- Vardenafil hydrochloride trihydrate (substance) [SNOMED CT concept]
- vardenafil hydrochloride trihydrate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Vardenafil hydrochloride trihydrate (substance) [SNOMED CT concept]
- vardenafil hydrochloride trihydrate [MeSH concept]
Validated automatic mappings to NTBT
- Vardenafil hydrochloride [SMS substance]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Vardenafil [NCIt concept]
is_salt_form_of
- Vardenafil [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients