Vardenafil - CISMeF

Preferred Label : Vardenafil;

NCIt definition : A benzenesulfonamide derivative and phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Vardenafil selectively inhibits PDE5, thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, prolonging penile erection.;

UNII : UCE6F4125H;

InChIKey : SECKRCOLJRRGGV-UHFFFAOYSA-N;

CAS number : 224785-90-4;

Chemical formula : C23H32N6O4S;

ChEBI ID : CHEBI:46295;

Details

Origin ID

C66650;

UMLS CUI

C0971579;

Currated CISMeF NLP mapping
- Vardenafil [LOINC component]
- Vardenafil [ICD-11 Extension code]
- Vardenafil [ICHI extension code]
- Vardenafil [SMS substance]
- Vardenafil (substance) [SNOMED CT concept]
- vardenafil [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing vardenafil (medicinal product) [SNOMED CT concept]
- Vardenafil [LOINC component]
- Vardenafil [ICD-11 Extension code]
- Vardenafil (substance) [SNOMED CT concept]
- vardenafil [ATC Code]
- vardenafil [MeSH concept]
Validated automatic mappings to BTNT
- Vardenafil Dihydrochloride [MeSH Descriptor]
- vardenafil [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Vardenafil Dihydrochloride [NCIt concept]
- Vardenafil Hydrochloride Trihydrate [NCIt concept]
is_free_acid_or_base_form_of
- Vardenafil Dihydrochloride [NCIt concept]
- Vardenafil Hydrochloride Trihydrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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