Porfimer - CISMeF

Preferred Label : Porfimer;

NCIt definition : A mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units, with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen radicals after activation by 630 nm wavelength laser light, resulting in tumor cell cytotoxicity. In addition, tumor cell death may occur due to ischemic necrosis secondary to vascular occlusion that appears to be partly mediated by the release of thromboxane A2.;

UNII : M15H03K69B;

Chemical formula : (C34H36N4O5)n.(C34H34N4O4)n;

ChEBI ID : CHEBI:60652;

Codes from synonyms : 412;

Details

Origin ID

C76306;

UMLS CUI

C0058031;

Currated CISMeF NLP mapping
- Porfimer [SMS substance]
- Porfimer (substance) [SNOMED CT concept]
- dihematoporphyrin ether [MeSH Descriptor]
- dihematoporphyrin ether [MeSH concept]
See also inter- (CISMeF)
- Product containing porfimer (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Porfimer Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Porfimer Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients