NCIt related terms : Photofrin II; photofrin; dihematoporphyrin ether;
NCIt definition : The sodium salt of a mixture of oligomers formed by ether and ester linkages of up
to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor
cells, porfimer produces oxygen radicals after activation by 630 nm wavelength laser
light, resulting in tumor cell cytotoxicity. In addition, tumor cell death may occur
due to ischemic necrosis secondary to vascular occlusion that appears to be partly
mediated by the release of thromboxane A2.;
Alternative definition : NCI-GLOSS: A drug used to treat some types of cancer. When absorbed by cancer cells
and exposed to light, porfimer sodium becomes active and kills the cancer cells. It
is a type of photodynamic therapy agent.;
UNII : Y3834SIK5F;
CAS number : 87806-31-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 87806-31-3
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G-SRS /a ;
Drug name : Photobarr;
Molecule name : CL-184116;
Chemical formula : (C34H35N4NaO5)n.(C34H33N4NaO4)n;
NCI Metathesaurus CUI : CL524033;
NSC code : 603062;
ChEBI ID : CHEBI:60773;
Codes from synonyms : CDR0000045291; NSC0603062; CDR0000046110; CDR0000046105; CDR0000045322;