Carbenicillin Indanyl

Preferred Label : Carbenicillin Indanyl;

NCIt definition : The indanyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Following absorption, carbenicillin indanyl is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.;

UNII : 5V278481KE;

InChIKey : JIRBAUWICKGBFE-MNRDOXJOSA-N;

CAS number : 35531-88-5;

Chemical formula : C26H26N2O6S;

ChEBI ID : CHEBI:52015;

Details

Origin ID

C76219;

UMLS CUI

C0054667;

Currated CISMeF NLP mapping
- Carindacillin [ICD-11 Extension code]
- Carindacillin [ICHI extension code]
- Carindacillin [SMS substance]
- carbenicillin indanyl [MeSH concept]
- carbenicillin indanyl [MeSH Supplementary Concept]
- carindacillin sodium [Substance BNPC]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Carindacillin [ICD-11 Extension code]
- carbenicillin indanyl [MeSH Supplementary Concept]
- carbenicillin indanyl [MeSH concept]
- carindacillin [ATC Code]
- carindacillin sodium [Substance BNPC]
Validated automatic mappings to BTNT
- Carbenicillin indanyl sodium (substance) [SNOMED CT concept]
- Carindacillin sodium [SMS substance]
- carindacillin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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