" /> Carbenicillin Indanyl Sodium - CISMeF





Preferred Label : Carbenicillin Indanyl Sodium;

NCIt related terms : Geocillin;

NCIt definition : The sodium salt of indanyl carbenicillin, a broad-spectrum, semi-synthetic carboxypenicillin antibiotic with bactericidal activity. Carbenicillin acylates C-terminal domain of penicillin-sensitive transpeptidase, resulting in opening the lactam ring of the antibiotic. This inactivation prevents the formation of the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. As a result, cell wall integrity is compromised and cell lysis may follow. This agent is used mainly for gram-negative infections, and has limited gram-positive coverage.;

UNII : 4OUL81K2RT;

InChIKey : QFWPXOXWAUAYAB-XZVIDJSISA-M;

CAS number : 26605-69-6;

Drug name : Geocillin;

Chemical formula : C26H25N2O6S.Na;

ChEBI ID : CHEBI:31358;

Codes from synonyms : NSC0528986;

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Keyword's position in hierarchy(ies) : arborescence

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28/05/2025


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