Apalcillin Sodium

Preferred Label : Apalcillin Sodium;

NCIt definition : The sodium salt of a naphthydridine derivative of the broad spectrum, semisynthetic ampicillin with antibacterial activity. Apalcillin specifically binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.;

UNII : 3XQ12NYC0Q;

InChIKey : DIGBQDMXLUJMHN-FSWJYKAZSA-M;

CAS number : 58795-03-2;

Chemical formula : C25H22N5O6S.Na;

ChEBI ID : CHEBI:51697;

Details

Origin ID

C76218;

UMLS CUI

C0771721;

Currated CISMeF NLP mapping
- Apalcillin sodium [SMS substance]
- apalcillin sodium [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- apalcillin sodium [MeSH concept]
Validated automatic mappings to NTBT
- apalcillin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Apalcillin [NCIt concept]
is_salt_form_of
- Apalcillin [NCIt concept]

Keyword's position in hierarchy(ies) :

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