Apalcillin - CISMeF

Preferred Label : Apalcillin;

NCIt definition : A naphthydridine derivative of the broad spectrum, semisynthetic ampicillin with antibacterial activity. Apalcillin specifically binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.;

UNII : 3373RT9U7A;

InChIKey : XMQVYNAURODYCQ-SLFBBCNNSA-N;

CAS number : 63469-19-2;

Chemical formula : C25H23N5O6S;

ChEBI ID : CHEBI:51691;

Details

Origin ID

C76217;

UMLS CUI

C0052145;

Currated CISMeF NLP mapping
- Apalcillin [ICD-11 Extension code]
- Apalcillin [ICHI extension code]
- Apalcillin [SMS substance]
- apalcillin [MeSH concept]
- apalcillin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Apalcillin [ICD-11 Extension code]
- apalcillin [MeSH concept]
- apalcillin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Apalcillin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Apalcillin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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