Amdinocillin Pivoxil

Preferred Label : Amdinocillin Pivoxil;

NCIt definition : The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.;

UNII : 1WAM1OQ30B;

InChIKey : NPGNOVNWUSPMDP-HLLBOEOZSA-N;

CAS number : 32886-97-8;

Chemical formula : C21H33N3O5S;

ChEBI ID : CHEBI:51210;

Details

Origin ID

C76216;

UMLS CUI

C0002436;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Pivmecillinam [ICD-11 Extension code]
- Pivmecillinam (substance) [SNOMED CT concept]
- Product containing pivmecillinam (medicinal product) [SNOMED CT concept]
- amdinocillin pivoxil [Substance BNPC]
- amdinocillin pivoxil [MeSH Descriptor]
- amdinocillin pivoxil [MeSH concept]
- amdinocillin pivoxil [SNOMED Notion]
- pivmecillinam [ATC Code]
Validated automatic mappings to BTNT
- pivmecillinam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Amdinocillin [NCIt concept]
is_salt_form_of
- Amdinocillin [NCIt concept]

Keyword's position in hierarchy(ies) :

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