Amdinocillin - CISMeF

Preferred Label : Amdinocillin;

NCIt definition : A semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Given the fact that most beta-lactam penicillins bind almost exclusively to PBPs 1 and 3, amdinocillin is able to synergize with other penicillins in the treatment against bacterial infections.;

UNII : V10579P3QZ;

InChIKey : BWWVAEOLVKTZFQ-NTZNESFSSA-N;

CAS number : 32887-01-7;

Chemical formula : C15H23N3O3S;

ChEBI ID : CHEBI:51208;

Details

Origin ID

C65229;

UMLS CUI

C0002435;

Currated CISMeF NLP mapping
- Amdinocillin [LOINC component]
- Amdinocilline [ICD-11 Extension code]
- Amdinocilline [ICHI extension code]
- Mecillinam [ICD-11 Extension code]
- Mecillinam [ICHI extension code]
- Mecillinam [SMS substance]
- Mecillinam (substance) [SNOMED CT concept]
- amdinocillin [Substance BNPC]
- amdinocillin [MeSH Descriptor]
- amdinocillin [MeSH concept]
- amdinocillin [SNOMED Notion]
See also inter- (CISMeF)
- Amdinocilline [ICD-11 Extension code]
- Product containing mecillinam (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Amdinocillin [LOINC component]
- Mecillinam [ICD-11 Extension code]
- Mecillinam (substance) [SNOMED CT concept]
- Product containing mecillinam (medicinal product) [SNOMED CT concept]
- amdinocillin [Substance BNPC]
- amdinocillin [MeSH Descriptor]
- amdinocillin [MeSH concept]
- amdinocillin [SNOMED Notion]
- mecillinam [ATC Code]
Validated automatic mappings to BTNT
- mecillinam [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Amdinocillin Pivoxil [NCIt concept]
is_free_acid_or_base_form_of
- Amdinocillin Pivoxil [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients