Methyl-CpG-Binding Protein 2

Preferred Label : Methyl-CpG-Binding Protein 2;

NCIt synonyms : Methyl CpG Binding Protein 2; MeCP2; MeCP-2 Protein;

NCIt definition : Methyl-CpG-binding protein 2 (486 aa, 52 kDa) is encoded by the human MECP2 gene. This protein plays a role in the repression of transcription through binding methylated DNA.;

Details

Origin ID

C75729;

UMLS CUI

C1527852;

Currated CISMeF NLP mapping
- Methyl-CpG-Binding protein 2 [MeSH concept]
- methyl-cpg-binding protein 2 [MeSH Descriptor]
OMIM relation
- Methyl-cpg-binding protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MECP2 protein, human [MeSH Supplementary Concept]
- MECP2 protein, human [MeSH concept]
- Methyl-CpG-Binding protein 2 [MeSH concept]
- methyl-cpg-binding protein 2 [MeSH Descriptor]
gene_encodes_gene_product
- MECP2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_malfunction_associated_with_disease
- Rett Syndrome [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Methylation Regulation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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