Homeobox Protein TGIF1

Preferred Label : Homeobox Protein TGIF1;

NCIt synonyms : 5'-TG-3'-Interacting Factor 1;

NCIt definition : Homeobox protein TGIF1 (401 aa, 43 kDa) is encoded by the human TGIF1 gene. This protein plays a role in both signal transduction and the negative regulation of transcription.;

NCIt note : Homeobox protein TGIF1 binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter. (UniProt);

Details

Origin ID

C75420;

UMLS CUI

C2697615;

OMIM relation
- Transforming growth factor-beta-induced factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TGIF1 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_is_element_in_pathway
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Holoprosencephaly Type 4 [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Development [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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