Sertaconazole - CISMeF

Preferred Label : Sertaconazole;

NCIt synonyms : [R,S]-( /-)-1-{2,4-Dichlor-beta-[(7-chlorbenzo[b]thien-3-yl)methoxy]phenethyl}imidazol;

NCIt definition : A synthetic imidazole derivative, containing a benzothiophene ring, with antifungal, antibacterial, anti-inflammatory and anti-pruritic activity. Besides its ability to inhibit the synthesis of ergosterol, the benzothiophene ring of sertaconazole is able to insert into the fungal cell wall instead of tryptophan. This increases the permeability of the cell wall. In addition, sertaconazole suppresses the release of cytokines.;

UNII : 72W71I16EG;

InChIKey : JLGKQTAYUIMGRK-UHFFFAOYSA-N;

CAS number : 99592-32-2;

Chemical formula : C20H15Cl3N2OS;

Details

Origin ID

C75206;

UMLS CUI

C0074391;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing sertaconazole (medicinal product) [SNOMED CT concept]
- Sertaconazole (substance) [SNOMED CT concept]
- sertaconazole [ATC Code]
- sertaconazole [ATC Code]
- sertaconazole [MeSH Supplementary Concept]
- sertaconazole [MeSH concept]
Validated automatic mappings to BTNT
- sertaconazole [ATC Code]
- sertaconazole [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Sertaconazole Nitrate [NCIt concept]
is_free_acid_or_base_form_of
- Sertaconazole Nitrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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