" /> Sertaconazole Nitrate - CISMeF





Preferred Label : Sertaconazole Nitrate;

NCIt synonyms : Dermofix; Zalain; 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, Mononitrate;

NCIt definition : The nitrate salt form of sertaconazole, a synthetic imidazole derivative with antifungal property. Sertaconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and the inhibition of ergosterol synthesis, an essential component of the cell membrane of fungi. This leads to a disruption of cell membrane permeability and leakage of adenine triphosphate (ATP) and other constituents from fugal cells.;

UNII : 1DV05410M5;

InChIKey : HAAITRDZHUANGT-UHFFFAOYSA-N;

CAS number : 99592-39-9;

Drug name : Ertaczo;

Chemical formula : C20H15Cl3N2OS.HNO3;

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29/05/2025


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