" /> Piroxicam - CISMeF





Preferred Label : Piroxicam;

NCIt synonyms : 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboximide-1,1-dioxide; PXM;

NCIt definition : A nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. As a non-selective, nonsteroidal anti-inflammatory drug (NSAID), piroxicam binds and chelates both isoforms of cyclooxygenases (COX1 and COX2), thereby stalling phospholipase A2 activity and conversion of arachidonic acid into prostaglandin precursors at the rate limiting cyclooxygenase enzyme step. This results in inhibition of prostaglandin biosynthesis. As a second, independent effect, piroxicam inhibits the activation of neutrophils thereby contributing to its overall anti-inflammatory effects.;

UNII : 13T4O6VMAM;

InChIKey : QYSPLQLAKJAUJT-UHFFFAOYSA-N;

CAS number : 36322-90-4;

Drug name : Feldene;

Chemical formula : C15H13N3O4S;

NSC code : 666076;

ChEBI ID : CHEBI:8249;

Codes from synonyms : NSC0666076; 00355;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
09/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.