Piroxicam - CISMeF

Preferred Label : Piroxicam;

NCIt synonyms : 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboximide-1,1-dioxide; PXM;

NCIt definition : A nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. As a non-selective, nonsteroidal anti-inflammatory drug (NSAID), piroxicam binds and chelates both isoforms of cyclooxygenases (COX1 and COX2), thereby stalling phospholipase A2 activity and conversion of arachidonic acid into prostaglandin precursors at the rate limiting cyclooxygenase enzyme step. This results in inhibition of prostaglandin biosynthesis. As a second, independent effect, piroxicam inhibits the activation of neutrophils thereby contributing to its overall anti-inflammatory effects.;

UNII : 13T4O6VMAM;

InChIKey : QYSPLQLAKJAUJT-UHFFFAOYSA-N;

CAS number : 36322-90-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 36322-90-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Feldene;

Chemical formula : C15H13N3O4S;

NSC code : 666076;

ChEBI ID : CHEBI:8249;

Codes from synonyms : NSC0666076; 00355;

Details

Origin ID

C751;

UMLS CUI

C0031990;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Piroxicam [ICD-11 Extension code]
- Piroxicam [LOINC component]
- Piroxicam (substance) [SNOMED CT concept]
- Product containing piroxicam (medicinal product) [SNOMED CT concept]
- piroxicam [ATC Code]
- piroxicam [ATC Code]
- piroxicam [ATC Code]
- piroxicam [Substance BNPC]
- piroxicam [MeSH Descriptor]
- piroxicam [SNOMED Notion]
- piroxicam [MeSH concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C9 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Eflornithine/Piroxicam [NCIt concept]
- Interferon Alfa/Piroxicam [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients