" /> Aminopterin Sodium - CISMeF





Preferred Label : Aminopterin Sodium;

NCIt synonyms : Sodium Aminopterin;

NCIt definition : The sodium salt of a pterin derivative with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. (NCI04);

UNII : FZU1QI13O9;

CAS number : 58602-66-7;

Chemical formula : C19H18N8O5.2Na;

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28/07/2025


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