Teloxantrone Hydrochloride

Preferred Label : Teloxantrone Hydrochloride;

NCIt synonyms : Moxantrazole Hydrochloride; Anthra(1,9-cd)pyrazol-6(2H)-one,7,10-dihydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-(methylamino)ethyl)amino) Dihydrochloride; CI-937 Hydrochloride;

NCIt definition : The hydrochloride salt of an anthrapyrazole antineoplastic antibiotic. Teloxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, as well as RNA and protein synthesis;

UNII : 7ZQK8VIO6V;

InChIKey : UMDBGTRUNWFBPE-UHFFFAOYSA-N;

CAS number : 132937-88-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 132937-88-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : DUP 937;

Chemical formula : C21H25N5O4.2HCl.H2O;

NSC code : 355644;

Details

Origin ID

C74544;

UMLS CUI

C0970561;

Currated CISMeF NLP mapping
- teloxantrone hydrochloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- teloxantrone hydrochloride [MeSH concept]
Validated automatic mappings to NTBT
- teloxantrone [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Teloxantrone [NCIt concept]
is_salt_form_of
- Teloxantrone [NCIt concept]

Keyword's position in hierarchy(ies) :

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