Teloxantrone - CISMeF

Preferred Label : Teloxantrone;

NCIt synonyms : Moxantrazole; Anthra(1,9-cd)pyrazol-6(2H)-one,7,10-dihydroxy-2-(2-((2-hydroxyethyl)amino)ethyl)-5-((2-(methylamino)ethyl)amino)-;

NCIt definition : An anthrapyrazole antineoplastic antibiotic. Teloxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, as well as RNA and protein synthesis;

UNII : 96521WL61B;

InChIKey : XASBSYHEEHVCSJ-UHFFFAOYSA-N;

CAS number : 91441-48-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 91441-48-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : CI-937;

Chemical formula : C21H25N5O4;

Details

Origin ID

C1520;

UMLS CUI

C0244823;

Currated CISMeF NLP mapping
- teloxantrone [MeSH concept]
- teloxantrone [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- teloxantrone [MeSH concept]
- teloxantrone [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Teloxantrone Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Teloxantrone Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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