Phosphodiesterase Inhibitor

Preferred Label : Phosphodiesterase Inhibitor;

NCIt synonyms : PDE Inhibitor;

NCIt definition : Any substance that inhibits phosphodiesterase, an enzyme that catalyzes the breaking of a phosphodiester bond. Usually, this refers to cyclic nucleotide phosphodiesterase, an enzyme that breaks the phosphodiester bond in the second messenger molecules cAMP and cGMP. Inhibition of cyclic nucleotide phosphodiesterase can be used to affect vasodilation.;

ChEBI ID : CHEBI:50218;

Details

Origin ID

C744;

UMLS CUI

C0031638;

Automatic exact mappings (from CISMeF team)
- Phosphodiesterase inhibitor (disposition) [SNOMED CT concept]
- Phosphodiesterase inhibitors [ICD-11 Extension code]
- Product containing phosphodiesterase inhibitor (product) [SNOMED CT concept]
- Substance with phosphodiesterase inhibitor mechanism of action (substance) [SNOMED CT concept]
- negative regulation of cyclic-nucleotide phosphodiesterase activity [GO term]
Currated CISMeF NLP mapping
- phosphodiesterase inhibitors [ATC Code]
- phosphodiesterase inhibitors [MeSH Descriptor]
- phosphodiesterase inhibitors [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing phosphodiesterase inhibitor (product) [SNOMED CT concept]
- Substance with phosphodiesterase inhibitor mechanism of action (substance) [SNOMED CT concept]
- phosphodiesterase inhibitors [MeSH concept]
- phosphodiesterase inhibitors [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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