" /> Avanafil - CISMeF





Preferred Label : Avanafil;

NCIt synonyms : (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide;

NCIt definition : An orally available phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Avanafil selectively inhibits PDE5, thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa of the penis. The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, thereby prolonging penile erection.;

UNII : DR5S136IVO;

InChIKey : WEAJZXNPAWBCOA-INIZCTEOSA-N;

CAS number : 330784-47-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 330784-47-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Stendra;

Molecule name : TA 1790; TA-1790;

Chemical formula : C23H26ClN7O3;

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07/05/2024


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